True or False: It is prohibited to vent an appliance through a pipe chase.

Ventilating an appliance through a pipe chase is generally prohibited because it can pose significant safety hazards. A pipe chase, which typically contains piping and other utilities that run vertically or horizontally within a building, can create pathways where combustion gases may not adequately disperse. This can lead to the accumulation of harmful gases like carbon monoxide within the building's structure, creating a serious health risk for occupants.

Furthermore, regulations are designed to ensure that venting systems are installed in such a manner that they promote proper air flow and venting of combustion byproducts. Such measures are crucial to maintaining indoor air quality and the safety of the living environment.

Local codes may further stipulate specific requirements regarding venting practices. However, the overarching guideline is the prohibition of venting through confined spaces such as pipe chases without appropriate protective measures in place, thus affirming the correctness of the statement.

While the other options may imply variability based on circumstances or local regulations, the fundamental safety concerns present in most code requirements lead to a consensus against venting this way.